SGL5213-DataSheet-MedChemExpress

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SGL5213Cat. No.:

HY-114308CAS No.:

1240305-17-2Molecular Formula:

C??H??N?O?Molecular Weight:

669.85Target:

SGLT Pathway:

Membrane Transporter/Ion Channel Storage:Please store the product under the recommended conditions in the COA.BIOLOGICAL ACTIVITY

Description SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor,

with IC 50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2

diabetes treatment [1].

IC?? & Target IC50: 29nM/20 nM (hSGLT1/ hSGLT2)[1].

REFERENCES

[1]. Kuroda S, et al. Discovery of potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor SGL5213 for type 2 diabetes treatment. Bioorg Med Chem. 2019 Jan 15;27(2):394-409.

McePdfHeight

Caution: Product has not been fully validated for medical applications. For research use only.

Tel: 609-228-6898 Fax: 609-228-5909 E-mail: [email protected]

Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

Product Data Sheet

Inhibitors ?Agonists ?Screening Libraries

www.MedChemExpress.com 1

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  • www.vqhnth.tw true http://www.vqhnth.tw/wendangku/zes/fecg/jb2f68ccd79v/k31b765ce0508763231126fdb7738l.html report 1179 SGL5213Cat. No.:HY-114308CAS No.:1240305-17-2Molecular Formula:C??H??N?O?Molecular Weight:669.85Target:SGLT Pathway:Membrane Transporter/Ion Channel Storage:Please store the product under the recommended conditions in the COA
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