CKD-519-DataSheet-MedChemExpress

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CKD-519Cat. No.:

HY-116078CAS No.:

1402796-27-3Molecular Formula:

C??H??F?NO?Molecular Weight:

601.6Target:

CETP Pathway:

Metabolic Enzyme/Protease Storage:Please store the product under the recommended conditions in the COA.BIOLOGICAL ACTIVITY

Description CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor, which inhibits CETP-mediated

transfer of cholesteryl ester in human serum with an IC 50 of 2.3 nM [1].

IC?? & Target IC50: 2.3 nM (Cholesteryl ester transfer protein)[1]

REFERENCES

[1]. Kim CO, et al. Pharmacokinetics, pharmacodynamics and safety of CKD-519, a CETP inhibitor, in healthy subjects. Drug Des Devel Ther. 2016 Nov 15;10:3763-3770.

McePdfHeight

Caution: Product has not been fully validated for medical applications. For research use only.

Tel: 609-228-6898 Fax: 609-228-5909 E-mail: [email protected]

Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

Product Data Sheet

Inhibitors ?Agonists ?Screening Libraries

www.MedChemExpress.com 1

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