PROTAC-FLT-3-degrader-1-DataSheet-MedChemExpress

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PROTAC FLT-3 degrader 1Cat. No.:

HY-114323CAS No.:

2230826-81-8Molecular Formula:

C??H??N?O?S?Molecular Weight:

1020.23Target:

PROTAC Pathway:

PROTAC Storage:Please store the product under the recommended conditions in the COA.BIOLOGICAL ACTIVITY

Description PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC 50 0.6 nM. Anti-

proliferative activity; apoptosis induction [1].

IC?? & Target IC50: 0.6 nM (FLT-3 ITD)[1]

REFERENCES

[1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432.

McePdfHeight

Caution: Product has not been fully validated for medical applications. For research use only.

Tel: 609-228-6898 Fax: 609-228-5909 E-mail: [email protected]

Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

Product Data Sheet

Inhibitors ?Agonists ?Screening Libraries

www.MedChemExpress.com 1

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  • www.vqhnth.tw true http://www.vqhnth.tw/wendangku/z3s/f3cg/jefb966760bv/kf78a6529647d27284b73f3423638l.html report 1060 PROTAC FLT-3 degrader 1Cat. No.:HY-114323CAS No.:2230826-81-8Molecular Formula:C??H??N?O?S?Molecular Weight:1020.23Target:PROTAC Pathway:PROTAC Storage:Please store the product under the recommended conditions in the COA.BIOL
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